An ophthalmologist confirms diagnosis of hhcs. But too much iron or problems with utilizing, storing, or transporting iron properly can lead to vision loss in the form of conditions such as age-related macular degeneration and hyperferritinemia syndrome, according to recent research findings. Iron accumulates in the body with age because we continue to absorb it from our diets, but we excrete very little, Dunaief said. Avertissement, pour pouvoir consulter et répondre aux annonces de la catégorie "Rencontres coquines vous devez lire et accepter les affirmations suivantes : - Je suis majeur(e) (jai 18 ans révolus). While smoking, poor diet, and lack of exercise typically contribute to oxidation of the retina, research has found that iron may also increase a persons risk of AMD, according. Attachment, posted on Mon, June 20, 2016 by Kayla Wiles. Normally the RPE has ways to prevent iron from entering the retina when iron levels are high, but if iron export from cells is unregulated, iron may accumulate in the eye and degrade the macula. Deferiprone can protect the retinas of mice by entering the retina and removing iron from it, said Dunaief, whose lab is currently testing additional drugs to prevent iron accumulation in the eye. The macula, a small portion of the retina which is responsible for sharp and detailed vision, deteriorates over time when the retinal pigment epithelium (RPE) surrounding the macula oxidizes triggering an inflammatory response. If an hhcs patient is falsely diagnosed with hemochromatosis, phlebotomies used to remove excess iron from the body could make the person become iron deficient.
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